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Most cited journal articles on mononucleosis published in 2022

Here's a list of the most relevant research on mononucleosis, also know as "glandular fever"

Mononucleosis, also known as "mono" or "glandular fever," is an infection caused by the Epstein-Barr virus (EBV). Research on mononucleosis aims to understand the causes, symptoms, and treatment of the condition.

One area of research focuses on the epidemiology of mononucleosis, which is a common viral infection that primarily affects young adults. Studies have shown that the incidence of mononucleosis is highest in adolescence and young adulthood and that it is more common in certain populations, such as college students.

Another area of research examines the symptoms and complications of mononucleosis. The most common symptoms include fatigue, fever, sore throat, and swollen lymph nodes, but mononucleosis can also cause complications such as anemia, splenomegaly (enlarged spleen), and hepatitis. Some studies have also reported the association of mononucleosis with certain chronic conditions such as multiple sclerosis, lupus, and rheumatoid arthritis.

Research also examines the treatment of mononucleosis. There is no specific treatment for mononucleosis, and the infection usually resolves on its own within a few weeks to a few months. Treatment is mainly symptomatic and supportive, such as rest and pain relievers to alleviate symptoms.

Additionally, research has been done on the long-term effects of mononucleosis. Studies have shown that most people fully recover from mono, but some people may experience prolonged fatigue or other symptoms months after the infection.

Overall, research on mononucleosis aims to understand the causes, symptoms, and treatment of the condition, as well as its impact on the health and well-being of individuals. While there is no specific treatment for mononucleosis, studies have shown that it is usually self-limiting and that the majority of people recover fully.

DOI: 10.1126/scitranslmed.abf3685
2022
Cited 11 times
A bivalent Epstein-Barr virus vaccine induces neutralizing antibodies that block infection and confer immunity in humanized mice
Chih Jen Wei, Wei Bu, Laura A Nguyen, Joseph D. Batchelor, JungHyun Kim, Stefania Pittaluga, James R. Fuller, Hanh Nguyen, Te Hui Chou, Jeffrey I. Cohen, Gary J. Nabel
Antibody
Virology
Immune system
DOI: 10.1016/j.coviro.2021.11.013
2022
Cited 9 times
Epigenetic control of the Epstein-Barr lifecycle
Rui Guo, Benjamin E. Gewurz
Biology
Epigenetics
Lytic cycle
DOI: 10.1016/j.xcrm.2022.100658
2022
Cited 7 times
Immunization with a self-assembling nanoparticle vaccine displaying EBV gH/gL protects humanized mice against lethal viral challenge
Harman Malhi, Leah J. Homad, Yu-Hsin Wan, Bibhav Poudel, Brooke Fiala, Andrew J. Borst, Jing Wang, Carl Walkey, Jason R. Price, Abigail Wall, Suruchi Singh, Zoe Moodie, Lauren Carter, Simran Handa, Colin Correnti, Barry L. Stoddard, David Veesler, Marie Pancera, James M. Olson, Neil A. King, Andrew T. McGuire
Immunogenicity
Virology
Immunization
DOI: 10.1080/09273948.2020.1811351
2022
Cited 5 times
Delayed-onset Bilateral Peripheral Posterior Interstitial Keratitis Associated with Epstein-Barr Virus-Induced Infectious Mononucleosis
Alfonso Iovieno, Marco Coassin, Fabiana Viscogliosi, Chantal Adani, Luca Cimino, Luigi Fontana
Medicine
Mononucleosis
Keratitis
DOI: 10.1093/brain/awac092
2022
Cited 4 times
Polygenic risk score association with multiple sclerosis susceptibility and phenotype in Europeans
Hengameh Shams, Xiaorong Shao, Adam Santaniello, Gina Kirkish, Adil Harroud, Qin Ma, Noriko Isobe, Catherine Schaefer, Jacob L. McCauley, Bruce A.C. Cree, Alessandro Didonna, Sergio E. Baranzini, Nikolaos A. Patsopoulos, Stephen L. Hauser, Lisa F. Barcellos, Roland G. Henry, Jorge R. Oksenberg
Multiple sclerosis
Genome-wide association study
Polygenic risk score
DOI: 10.1016/s1474-4422(22)00086-2
2022
Cited 4 times
Epstein-Barr virus and multiple sclerosis: supporting causality
Francesca Aloisi, Marco Salvetti
Mononucleosis
Multiple sclerosis
Epstein–Barr virus
DOI: 10.3389/fimmu.2022.937583
2022
Cited 4 times
Infectious mononucleosis is associated with an increased incidence of multiple sclerosis: Results from a cohort study of 32,116 outpatients in Germany
Sven H. Loosen, Corinna Doege, Sven G. Meuth, Tom Luedde, Karel Kostev, Christoph Roderburg
Mononucleosis
Incidence (geometry)
Medicine
DOI: 10.1016/j.jmii.2021.10.002
2022
Cited 4 times
Cytomegalovirus proctitis in non-human immunodeficiency virus infected patients: A case report and literature review
Kai Liu, Hsiao-Tuan Chao, Yen Yu Lu, Ying Su, Wen Sen Lee
Medicine
Cytomegalovirus
Proctitis
DOI: 10.3389/fped.2021.809005
2022
Cited 3 times
Clinical Characteristics and the Risk Factors of Hepatic Injury in 221 Children With Infectious Mononucleosis
Chao Zhang, Shu Cui, Guo-Shun Mao, Guitao Li
Mononucleosis
Medicine
Internal medicine
DOI: 10.1080/07448481.2020.1726927
2022
Cited 3 times
Epstein-Barr virus infection status among first year undergraduate university students
Allen B. Choi, Kathryn S. Marcus, Danielle Pohl, Patrick Ten Eyck, Henry H. Balfour, J. Brooks Jackson
Mononucleosis
Immunology
Medicine
DOI: 10.1016/j.jhep.2021.09.011
2022
Cited 3 times
Multicenter study on recent portal venous system thrombosis associated with cytomegalovirus disease
Chloé De Broucker, Aurélie Plessier, Isabelle Ollivier-Hourmand, Sébastien Dharancy, Christophe Bureau, Jean-Paul Cervoni, Philippe Sogni, Odile Goria, Olivier Corcos, Riccardo Sartoris, Maxime Ronot, Valérie Vilgrain, Emmanuelle de Raucourt, Kamal Zekrini, Hortense Davy, François Durand, Audrey Payancé, Nadira Fidouh-Houhou, Yazdan Yazdanpanah, Dominique Valla, Pierre-Emmanuel Rautou
Medicine
Gastroenterology
Internal medicine
DOI: 10.3389/fneur.2022.887794
2022
Cited 3 times
The Potential for EBV Vaccines to Prevent Multiple Sclerosis
P. A. C. Maple, Alberto Ascherio, Jeffrey A. Cohen, Gary Cutter, Gavin Giovannoni, Claire Shannon-Lowe, Radu Tanasescu, Bruno Gran
Medicine
Immunology
Epstein–Barr virus
DOI: 10.3389/fimmu.2021.789604
2022
Tree Shrew Is a Suitable Animal Model for the Study of Epstein Barr Virus
Wei Xia, Honglin Chen, Yiwei Feng, Nan Shi, Zong-jian Huang, Qingyuan Feng, Xu Jiang, Guangyao He, Maohai Xie, Lai Yongjing, Zhi Wang, Xiang Yi, Anzhou Tang
Biology
Virology
Virus
DOI: 10.1016/j.ecoenv.2022.113470
2022
ZEA and DON inhibited inflammation after L. monocytogenes infection and induced ribosomal hyperfunction
Guodong Cai, Fang Zhong, Qianying Cao, Yuni Bai, Hui Zou, Jianhong Gu, Yan Yuan, Guoqiang Zhu, Zongping Liu, Jianchun Bian
Proinflammatory cytokine
Inflammation
Biology
DOI: 10.3390/pathogens11080864
2022
Progress in Prophylactic and Therapeutic EBV Vaccine Development Based on Molecular Characteristics of EBV Target Antigens
Marija Rozman, Petra Korać, Karlo Jambrosic, Snježana Židovec Lepej
Virology
Epstein–Barr virus
Mononucleosis
DOI: 10.1016/j.ajoc.2022.101363
2022
A case of Epstein-Barr virus acute retinal necrosis successfully treated with foscarnet
Kayo Suzuki, Kenichi Namba, Keitaro Hase, Kazuomi Mizuuchi, Daiju Iwata, Takako Ito, Nobuyoshi Kitaichi, Hiroshi Takase, Susumu Ishida
Medicine
Foscarnet
Acute retinal necrosis
DOI: 10.1128/jvi.01434-21
2022
“M1 macrophage polarization prevails in EBV infected children in an immuneregulatory environment”
A Moyano, N.M. Ferressini Gerpe, E De Matteo, M V Preciado, Paola Andrea Chabay
Macrophage polarization
Mononucleosis
Biology
DOI: 10.1016/j.virs.2022.07.007
2022
Epidemiological characteristics and disease burden of infectious mononucleosis in hospitalized children in China: A nationwide retrospective study
Mengjia Liu, Xinyu Wang, Linlin Zhang, Guoshuang Feng, Yue-Ping Zeng, Ran Wang, Zhengde Xie
Medicine
Mononucleosis
Epidemiology
DOI: 10.12659/ajcr.934003
2022
Relapsing Infectious Mononucleosis-Like Symptoms Associated with Liver Insufficiency in a Chronic Hepatitis B Patient with Common Variable Immunodeficiency
Akira Sato, Fumiaki Sano, Hideaki Takahashi, Nobuyuki Matsumoto
Common variable immunodeficiency
Medicine
Mononucleosis
DOI: 10.1016/j.msard.2022.103561
2022
Markers of Epstein-Barr virus and Human Herpesvirus-6 infection and multiple sclerosis clinical progression
Chunrong Tao, Steve Simpson, Bruce V. Taylor, Leigh Blizzard, Robyn M. Lucas, Anne-Louise Ponsonby, Simon Broadley, Ingrid van der Mei
Multiple sclerosis
Medicine
Internal medicine
DOI: 10.3389/fimmu.2022.867918
2022
Four Decades of Prophylactic EBV Vaccine Research: A Systematic Review and Historical Perspective
Gabriela M. Escalante, Lorraine Z. Mutsvunguma, Murali Muniraju, Esther Rodríguez, Javier Gordon Ogembo
Medicine
Immunology
Clinical trial
DOI: 10.1002/mgg3.1873
2022
Exon skipping caused by a complex structural variation in SH2D1A resulted in X‐linked lymphoproliferative syndrome type 1
Liwen Wu, Feng Yang, Jia Wang, Fan Yang, Mengmeng Liang, Haiyan Yang
Immune dysregulation
Hemophagocytic lymphohistiocytosis
Exome sequencing
DOI: 10.1186/s12879-022-07116-9
2022
Epstein–Barr virus-associated infectious mononucleosis with acute epididymitis: a case report
Kentaro Sako, Tsuneaki Kenzaka, Ayako Kumabe
Mononucleosis
Medicine
Pharyngitis
DOI: 10.7860/jcdr/2022/53011.16074
2022
White Blood Cells in COVID-19: A Study on Viral Induced Cytopathic Changes in the Peripheral Smear
Nidha Gaffoor, Archana Shetty, Aparna Muralidhar, Jessica Minal, Nikhil P, Hima Sree Edupuganti
Neutrophilia
Medicine
White blood cell
DOI: 10.3389/fimmu.2022.1027859
2022
Case report: Systemic muscle involvement as the primary clinical manifestation of chronic active Epstein–Barr virus infection: A case-based review
Shanfen Shi, Liangda Li, Cuiping Pan, Yandi Yang, Gun Chen, Yongping He
Polymyositis
Myositis
Medicine